by Rishikesh Narayan, Jonathan O. Bauer, Carsten Strohmann, Andrey P. Antonchick*, Herbert Waldmann*
Dipolar cycloaddition: A highly efficient
copper(I)-catalyzed enantioselective [3+2] cycloaddition reaction of 1,3-fused
cyclic azomethine ylides and nitroalkenes has been developed. This method
provides access to functionalized tropane scaffolds with several quaternary and
tertiary stereocenters in a single step under mild reaction conditions.
Angewandte Chemie International Edition
Article first published online: 21 OCT 2013
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