Wednesday, October 9, 2013

Part I: The Development of the Catalytic Wittig Reaction

by Christopher J. O'Brien,* Zachary S. Nixon, Andrew J. Holohan, Stephen R. Kunkel, Jennifer L. Tellez, Bryan J. Doonan, Emma E. Coyle, Florie Lavigne, Lauren J. Kang, Katherine C. Przeworski


Part I: The Development of the Catalytic Wittig Reaction

We have developed the first catalytic (in phosphane) Wittig reaction (CWR). The utilization of an organosilane was pivotal for success as it allowed for the chemoselective reduction of a phosphane oxide.

Chem. Eur. J.

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